Introduction Orfamide A is a cyclic lipodepsipeptide produced by non-ribosomal peptide synthetases in various Pseudomonas species. It is the name-sake CLiP of a group of structurally similar lipopeptides, the orfamide group. This group also contains orfamides B, orfamide C (Gross, 2007), orfamides D – G (Ma, 2016), orfamide H (Ma, 2019), orfamides J – M [...]